She began her career in entertainment as a lively traffic reporter for CALTEX’s “RoadWatch” in 1999. Guanio caught the attention of travelogue channel Lakbay TV and her career has been on the move ever since. After Lakbay TV, Guanio was one of the hosts of ABS-CBN’s morning show “Alas Singko Y Medya”. Her biggest career move though was when she transferred from the Kapamilya network to the GMA Network. Guanio married businessman Steve Mago in October 2011. She give birth to her first child, Scarlet Jenine, on August 2012 and went on a three month hiatus on “24 Oras”.