In 2013 she starred as Ava Hessington in the TV series Suits. In 2014 she starred in the TV series 24: Live Another Day as Margot Al-Harazi. Fairley starred as Mrs. Granger in the 2010 movie Harry Potter and the Deathly Hallows: Part 1. She was nominated for an Olivier Award for her role in the stage production of Othello. Fairley won an Irish Film and Television Award for Best Supporting Actress – Television for Game of Thrones in 2014. She has also been nominated for a Screen Actors Guild Award and a Saturn Award for the same role.